Abstract:
Recent research has shown evidence of functional connectivity in rodents, indicating the potential of using rats as a model for human resting state connectivity. A potential confound of using a rat model is the necessary use of anesthesia. This study employs cross-correlation, principle component analysis, and independent component analysis to compare the connectivity between contralateral somatosensory cortices in rats anesthetized with alphachloralose, isoflurane, and medetomine hydrochloride.
Reference:
abstract K. A. Williams, S. M. LaConte, S. J. Peltier, S. D. Keilholz. Investigating the influence of anesthesia on resting state connectivity in rats using multiple analysis techniques. In Proceedings 15th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Berlin, page 2009, 2007. [bibtex]
Bibtex Entry:
@inproceedings{Berlin2009,
Author = {Williams, K. A. and LaConte, S. M. and Peltier, S. J. and Keilholz, S. D.},
Title ={Investigating the influence of anesthesia on resting state connectivity in rats using multiple analysis techniques},
BookTitle = {Proceedings 15th Scientific Meeting, International Society for Magnetic Resonance in Medicine, Berlin},
Pages = {2009},
Abstract = {Recent research has shown evidence of functional connectivity in rodents, indicating the potential of using rats as a model for human resting state connectivity. A potential confound of using a rat model is the necessary use of anesthesia. This study employs cross-correlation, principle component analysis, and independent component analysis to compare the connectivity between contralateral somatosensory cortices in rats anesthetized with alphachloralose, isoflurane, and medetomine hydrochloride.},
Keywords = {Berlin2009},
Year = {2007} }